Generic Levitra is an oral drug used to treat erectile
dysfunction. Sexual stimulation causes the production and release of nitric
oxide from the nerves endings of the cavernous bodies of the penis hereby
activating enzyme Guanylate cyclase.
Guanylate cyclase in its turn is responsible for production
of cyclic guano sine monophosphate (cGMP). The cGMP causes widening and
relaxation of the blood vessels carrying blood to the penis. Generic Levitra
prevents phosphodiesterase-5 enzyme from destroying cGMP and thus helps to
support blood flow to the penis.
Dosage and Direction:
The recommended dose of Generic Levitra is 10 mg per day
taken an hour before intercourse.
If no side effects
are experienced the dosage can be increased up to 20 mg.
In case of adverse
effects the dose is reduced to 5 mg daily.
Do not take more than one tab of Generic Levitra a day.
Precautions:
Generic Levitra has not been studied in people with
cardiovascular disease, so it is preferable to avoid
Generic Levitra if in
patients who have a stroke or heart failure, or a heart attack in history and
especially within last six month.
Before to take Generic Levitra inform your
doctor if you have kidney or liver problems, a bleeding disorder, stomach
ulcer, or an inherited retinal disorder such as retinitis pigmentosa, allergic
reaction to this medicine or any other medicines, deformation of the penis such
as angulation, cavernous fibrosis (Peyronie's disease), as well as in diseases
that contribute to the development of priapism (sickle-cell anemia, multiple
myeloma, leukemia, or leukemia).
Contraindications:
Generic Levitra is contraindicated in patients with
hypersensitivity to its ingredients, ones treated with organic nitrates, in
patients under 16 y.o., or those who take HIV protease inhibitors such as
indinavir and ritonavir.
Possible Side Effect:
Generic Levitra is usually well tolerated and side effects
if occur are transient.
The most frequent side effects are: headache, flushing
(hyperemia of the person); frequent; dizziness, diarrhea phenomenon, nausea,
nasal congestion.
More rare and
uncommon adverse effects are photosensitivity of skin, hypertension, back pain,
watery eyes, hypotension, myalgia, priapism.
Drug Interaction:
Generic Levitra's metabolism is inhibited by erythromycin,
ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and
ritonavir (Norvir).
Generic Levitra reduces the concentration of ritonavir and
indinavir. In patients treated with nitrates Generic Levitra may aggravate
chest pain by increasing heart rate and lowering blood pressure.
Generic
Levitra is able to exaggerate the blood pressure lowering effects of
alpha-blocking drugs (terazosin or Hytrin). Generic Levitra never should be
administered in patients who are treated with organic nitrates.
Missed Dose:
Generic Levitra is taken when needed but not more often than
once daily so missed dose is not supposed.
Over Dose:
Symptoms of overdose include pain in the back, jaw, arm,
blindness, blurred vision, chest pain or discomfort, decreased vision, blurred
vision.
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